Royal Air Force Typhoon FGR4s have conducted a mission with French aircraft in a coordinated attack on an hidden munitions depot in Syria used by the Daesh militant organization, per a report from the British defence ministry.
The facility, located using intelligence, was believed to be housing weapons and explosive materials, the statement said, and was located in mountains just above Palmyra in central Syria.
"The RAF jets employed laser-guided Paveway IV weapons to strike a several entry passages down to the facility... preliminary assessments are that the objective was successfully hit," the MoD said.
There was no sign of any civilian impact in the attack late on Saturday and each participating jet returned to base without incident, the MoD added.
The Typhoon FGR4s were supported by a Voyager tanker plane.
Daesh - alternatively referred to as ISIS - imposed jihadist rule over parts of Syria and Iraq prior to its 2019 collapse.
"This strike shows our UK leadership, and commitment to work closely with allied nations, to eradicate any revival of the terrorist group and their harmful and extremist ideologies in the Middle East," UK Defence Secretary the minister remarked.
RAF aircraft have carried out patrols over Syria to "deter any attempted resurgence" of IS after its routing at the Baghuz confrontation in the year 2019, the MoD reported.
"I must thank every member of the UK armed forces participating in this operation for their skill and their valour," he added. "They were among a great many British troops on duty over the festive period. This action, to eliminate militants who threaten our safety, demonstrates how British military are always on standby, throughout the year, protecting the UK within its borders and strong abroad."
Last December, the American forces carried out what it called a "major assault" on Islamic State objectives in the country, after an ambush killed two US servicemembers and a local interpreter in the Palmyra area.
The UN reports IS still maintains between 5,000 and 7,000 combatants in Syria and Iraq.